Results 61 to 70 of about 1,361,107 (277)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Frontiers in Energy Research, 2022 In complex power systems, when power equipment fails, multiple concurrent failures usually occur instead of a single failure. Concurrent failures are so common and hidden in complex systems that diagnosis requires not only analysis of failure ...
Liqing Liu +8 more
doaj +1 more source
On the Approximation of Laplacian Eigenvalues in Graph Disaggregation
, 2016 Graph disaggregation is a technique used to address the high cost of computation for power law graphs on parallel processors. The few high-degree vertices are broken into multiple small-degree vertices, in order to allow for more efficient computation in
Hu, Xiaozhe +2 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
CSEE Journal of Power and Energy SystemsBy modeling the spatiotemporal data of the power grid, it is possible to better understand its operational status, identify potential issues and risks, and take timely measures to adjust and optimize the system. Compared to the bus-branch model, the node-
Peng Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Distinguishing Cartesian Powers of Graphs [PDF]
The Electronic Journal of Combinatorics, 2005 Given a graph $G$, a labeling $c:V(G) \rightarrow \{1, 2, \ldots, d\}$ is said to be $d$-distinguishing if the only element in ${\rm Aut}(G)$ that preserves the labels is the identity. The distinguishing number of $G$, denoted by $D(G)$, is the minimum $d$ such that $G$ has a $d$-distinguishing labeling.
openaire +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source