Results 51 to 60 of about 270,997 (279)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Path Laplacians versus fractional Laplacians as nonlocal operators on networks

open access: yesNew Journal of Physics, 2021
Here we study and compare nonlocal diffusion processes on networks based on two different kinds of Laplacian operators. We prove that a nonlocal diffusion process on a network based on the path Laplacian operator always converges faster than the standard
Ernesto Estrada
doaj   +1 more source

Heat kernel coefficients on Kahler manifolds [PDF]

open access: yes, 2016
Polterovich proved a remarkable closed formula for heat kernel coefficients of the Laplace operator on compact Riemannian manifolds involving powers of Laplacians acting on the distance function.
Liu, Kefeng, Xu, Hao
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Rainbow Connection Number of Graph Power and Graph Products [PDF]

open access: yesGraphs and Combinatorics, 2013
15 pages.
Basavaraju, Manu   +3 more
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Distance Powers and Distance Matrices of Integral Cayley Graphs over Abelian Groups [PDF]

open access: yes, 2012
It is shown that distance powers of an integral Cayley graph over an abelian group are again integral Cayley graphs over that group. Moreover, it is proved that distance matrices of integral Cayley graphs over abelian groups have integral ...
Klotz, W., Sander, T.
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Edge growth in graph powers [PDF]

open access: yes, 2012
For a graph G, its rth power G^r has the same vertex set as G, and has an edge between any two vertices within distance r of each other in G. We give a lower bound for the number of edges in the rth power of G in terms of the order of G and the minimal ...
Pokrovskiy, Alexey
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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