Results 61 to 70 of about 190,756 (265)
Auto-GNN: Neural architecture search of graph neural networks
Frontiers in Big Data, 2022 Graph neural networks (GNNs) have been widely used in various graph analysis tasks. As the graph characteristics vary significantly in real-world systems, given a specific scenario, the architecture parameters need to be tuned carefully to identify a ...
Kaixiong Zhou +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Monotonicity in graph searching [PDF]
Journal of Algorithms, 1991 Summary: We give a new proof of the result, due to A. LaPaugh, that a graph may be optimally ``searched'' without clearing any edge twice.
Bienstock, D., Seymour, Paul
openaire +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
A Method for LLM-Based Construction of a Materials Property Knowledge Graph: A Case Study
Applied SciencesIn the field of materials science, experimental data or simulation results on material properties are often unevenly distributed. In addition to the vast unexplored material space, properties of lesser interest have not been measured even for well ...
Michiko Yoshitake, Takahiro Nagata
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Introduction of some one-searchable graphs [PDF]
Mathematics and Computational SciencesSearch Graph problems are usually modeled in the form of On-Graph games between oneescaping thief and some police officers. Police intends to arrest the thief while the real goal of robber isprevention from arrest. As it has been evaluated in this paper,
mohammad taati
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MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source