Results 81 to 90 of about 358,315 (287)
Topological graph-based analysis of solid-state ion migration
npj Computational Materials, 2023 To accelerate the development of ion conducting materials, we present a general graph-theoretic analysis framework for ion migration in any crystalline structure.
Jimmy-Xuan Shen +4 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Connected Graph Searching in Outerplanar Graphs
Electronic Notes in Discrete Mathematics, 2005 Search games are a powerfull tool for studying various connectivity parameters of graphs. In the classical search game, we consider an undirected graph G = (V, E) whose edges are initially contaminated. A set of searchers try to clean the graph. At the beginning the graph contains no searchers.
Fedor V. Fomin +2 more
openaire +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
NEW ALGORITHM FOR SEARCHING CRITICAL PATHS IN GRAPH AND ITS APPLICATION
Наука и техника, 2008 The paper proposes a new algorithm for searching critical paths in a graph which is based on the idea of execution of ternary operations over a matrix of arch balance of the graph.
A. D. Korznikov
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Jixie chuandong, 2013 Nowadays,empirical formula method,table-searching method and enclosed graph method are the three main methods for choosing gear modification coefficient.The enclosed graph method of modification coefficient which takes all performance indexes into ...
侯克青, 徐荣, 张伟, 侯晓晨
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Chemical Engineering Transactions, 2018 The hydrothermal vent system will produces a large number of chemical plumes during the eruption process. Relevant characteristics of chemical plumes can be used to navigate underwater robots to achieve the source positioning.
Kaibo Zhu
doaj +1 more source