Results 51 to 60 of about 323,816 (328)

Graph neural fields: A framework for spatiotemporal dynamical models on the human connectome.

open access: yesPLoS Computational Biology, 2021
Tools from the field of graph signal processing, in particular the graph Laplacian operator, have recently been successfully applied to the investigation of structure-function relationships in the human brain.
Marco Aqil   +3 more
doaj   +1 more source

Quantum graph spectra of a graphyne structure

open access: yes, 2013
We study the dispersion relations and spectra of invariant Schr\"odinger operators on a graphyne structure (lithographite). In particular, description of different parts of the spectrum, band-gap structure, and Dirac points are provided.Comment: PDFLaTex,
Do, Ngoc T., Kuchment, Peter
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Representation and generation of plans using graph spectra [PDF]

open access: yes, 2007
Numerical comparison of spaces with one another is often achieved with set scalar measures such as global and local integration, connectivity, etc., which capture a particular quality of the space but therefore lose much of the detail of its overall ...
Hanna, S.
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Laplacian Spectral Characterization of Signed Sun Graphs

open access: yesTheory and Applications of Graphs, 2023
A sun SGn is a graph of order 2n consisting of a cycle Cn, n ≥ 3, to each vertex of it a pendant edge is attached. In this paper, we prove that unbalanced signed sun graphs are determined by their Laplacian spectra.
Fatemah Motialah   +1 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

On spectra of unitary Cayley mixed graph [PDF]

open access: yesTransactions on Combinatorics, 2016
‎‎‎‎In this paper we introduce mixed unitary Cayley graph $M_{n}$‎ ‎$(n>1)$ and compute its eigenvalues‎. ‎We also compute the energy of‎ ‎$M_{n}$ for some $n$‎.
Chandrashekar Adiga   +1 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Trace formulae for graph Laplacians with applications to recovering matching conditions [PDF]

open access: yes, 2014
Graph Laplacians on finite compact metric graphs are considered under the assumption that the matching conditions at the graph vertices are of either $\delta$ or $\delta'$ type. In either case, an infinite series of trace formulae which link together two
Alexander, V. Kiselev, Yulia Ershova
core  

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