Results 121 to 130 of about 7,041,985 (308)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Development of Graphcards a hypertext system for learning graph theory and graph algorithms
, 1998 GraphCards is a research project devoted to the development of a system for learning graph theory and implementing graph algorithms. It contains an information base for learning and referencing graph theory topics, integrated with an experimentation tool
Warty, Durgesh A.
core
The n-th Power Signed Graphs-II [PDF]
, 2010 For standard terminology and notion in graph theory we refer the reader to Harary [6]; the non-standard will be given in this paper as and when required.
Reddyy, P. Siva Kota +2 more
core +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Graph Theory Students’ Perceptions of Graph Isomorphism [PDF]
Iranian Journal of Educational ResearchObjective: Graph isomorphism is a central topic in graph theory, yet students often struggle to grasp its underlying principles. This study aimed to explore students' perceptions of graph isomorphism and identify the conceptual metaphors they employ when
Ali Jafari +2 more
doaj
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Graph theory with an introduction to algebraic graph theory [PDF]
, 2018 Firstly, we shall start with an introduction to the main topics in Graph Theory with special emphasis in connectivity, colorability and planarity. The, we shall continue with the firsts concepts in Algebraic Graph Theory.
Márquez Pérez, Alberto
core
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source