Results 41 to 50 of about 1,392,860 (268)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
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Graph Laplacians and Stabilization of Vehicle Formations [PDF]
, 2001 Control of vehicle formations has emerged as a topic of significant interest to the controls community. In this paper, we merge tools from graph theory and control theory to derive stability criteria for formation stabilization.
Fax, J. Alexander, Murray, Richard M.
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
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Comparative Study of Planar Octahedron Molecular Structure via Eccentric Invariants
Molecules, 2023 A branch of graph theory that makes use of a molecular graph is called chemical graph theory. Chemical graph theory is used to depict a chemical molecule. A graph is connected if there is an edge between every pair of vertices.
Zheng-Qing Chu +5 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Knowledge graph analysis of particles in Japanese [PDF]
, 2005 The theory of knowledge graphs is a structuralistic theory of language. Its ontology consists of eight types of binary relationships and four types of so-called frames. The relationships connect so-called tokens, that represent semantic units.
Hoede, C.
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Role of Graph Theory in System of Systems Engineering
IEEE Access, 2016 The world of system of systems engineering (SoSE), and consequently systems engineering, is currently being reformalized so as to provide greater functionality, integration, and extensibility into designed systems of systems (SoS).
Willie K. Harrison
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
, 2011 This is a replacement paper. There are 6 chapters. The first two chapters are introductory. The third chapter is on extremal graph theory. The fourth chapter is about algebra in graph theory. The fifth chapter is focused on algorithms. The third section of the fifth chapter deals with computable time.
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