Results 31 to 40 of about 573,680 (311)

The spectral power distribution prediction of LED light source based on Gaussian mathematical model and improved residual network

open access: yesScientific Reports
Accurate prediction of the spectral power distribution of light-emitting diodes in multi-phosphor systems is challenging because of the influence of material composition and operating conditions.
Lihui Wu   +5 more
doaj   +1 more source

Visual Research: An Introduction to Research Methodologies in Graphic Design [PDF]

open access: yes, 2005
"Visual Research: An Introduction to Research Methodologies in Graphic Design" is a guide to the practice of researching for graphic design projects. This book explains the key terms and theories that underlie design research; examining the importance of
Bestley, Russ, Noble, Ian
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Blogs, Reflective Practice and Autonomous Learning in Graphic Design Communication [PDF]

open access: yes, 2007
Since their inception in 2004 Blogs have become a major contributor to the development of the social networking phenomenon. This paper reports on a small qualitative research project utilising case studies of the use of blogs by Level2 BA Graphic Design ...
Maloney, Peter
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Design and simulation of gear transmission system based on metamaterial

open access: yesAIP Advances, 2023
In this research, we integrate a three-dimensional micro-/nano-lattice structure metamaterial with conventional helical gears using a composite method to reduce the vibration.
Shuihai Dou   +5 more
doaj   +1 more source

Review of Ultrasonic Particle Manipulation Techniques: Applications and Research Advances

open access: yesMicromachines, 2023
Ultrasonic particle manipulation technique is a non-contact label-free method for manipulating micro- and nano-scale particles using ultrasound, which has obvious advantages over traditional optical, magnetic, and electrical micro-manipulation techniques;
Shuai Wang   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

The power of GIS language [PDF]

open access: yes, 2018
I have been working now for 50 years – since the foundation of Environmental Systems Research Institute (Esri), in 1969 – on building software tools that help different kinds of users do their work better.
Dangermond, Jack, Pesaresi, Cristiano
core  

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