Results 41 to 50 of about 846,152 (303)

Visual Research: An Introduction to Research Methodologies in Graphic Design [PDF]

open access: yes, 2005
"Visual Research: An Introduction to Research Methodologies in Graphic Design" is a guide to the practice of researching for graphic design projects. This book explains the key terms and theories that underlie design research; examining the importance of
Bestley, Russ, Noble, Ian
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Visual Semiotic Analysis in Farm Animal Vocabulary Educational Videos for Early Childhood

open access: yesMimbar Ilmu
In the digital era, animated educational media has become an increasingly effective tool in early childhood learning. Nevertheless, research on how visual signs in educational videos can support the learning process remains very limited.
Annisa Bela Pertiwi, Budiman Budiman
doaj   +1 more source

Using digital storytelling as a methodology for the introduction of socially responsible graphic design in a University Bachelor of Computer Graphic Design Programme [PDF]

open access: yes, 2009
This paper case studies the pedagogical methodology for a digital storytelling project involving final semester Bachelor of Computer Graphic Design students and students from a community based charitable arts trust. A young artist is paired with a senior
Vanderschantz, Nicholas
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The composition of the two inscriptions in the courtyard of the Old Emami Isfahanie and Shahid Mashhadi [PDF]

open access: yesنگره, 2017
Old Courtyard is one of the oldest parts of the holy shrine of Imam Reza (AS) in which various methods of decorations are used. An important group of these decorations are inscriptions which are installed on the porticos and their pillars. Thuluth scroll
Samira Sadat Danandeh
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Women and the Making of the University of Alicante Campus: Critical Reappraisals of Modern Architecture (1982–1999)

open access: yesArts, 2020
A stroll around the University of Alicante campus is like a journey through the history of Spanish architecture of the last 40 years, as many of its buildings exemplify the best production of the period.
María-Elia Gutiérrez-Mozo   +2 more
doaj   +1 more source

Designing for Design Activity [PDF]

open access: yes, 2009
The area of graphic design has expanded since digital media was introduced, and it requires new creative thinking skills in the design process.
Kang, Sunghyun
core  

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