Results 41 to 50 of about 852,315 (263)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Visual Semiotic Analysis in Farm Animal Vocabulary Educational Videos for Early Childhood
Mimbar IlmuIn the digital era, animated educational media has become an increasingly effective tool in early childhood learning. Nevertheless, research on how visual signs in educational videos can support the learning process remains very limited.
Annisa Bela Pertiwi, Budiman Budiman
doaj +1 more source
Designing for Design Activity [PDF]
, 2009 The area of graphic design has expanded since digital media was introduced, and it requires new creative thinking skills in the design process.
Kang, Sunghyun
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The composition of the two inscriptions in the courtyard of the Old Emami Isfahanie and Shahid Mashhadi [PDF]
نگره, 2017 Old Courtyard is one of the oldest parts of the holy shrine of Imam Reza (AS) in which various methods of decorations are used. An important group of these decorations are inscriptions which are installed on the porticos and their pillars. Thuluth scroll
Samira Sadat Danandeh
doaj +1 more source
Using digital storytelling as a methodology for the introduction of socially responsible graphic design in a University Bachelor of Computer Graphic Design Programme [PDF]
, 2009 This paper case studies the pedagogical methodology for a digital storytelling project involving final semester Bachelor of Computer Graphic Design students and students from a community based charitable arts trust. A young artist is paired with a senior
Vanderschantz, Nicholas
core +1 more source
Research in graphic design [PDF]
, 2017 An invited and reviewed opinion piece about the current state of research in graphic/communication ...
Bateman J. A. +24 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Spin/3 Magazine: Action Time Vision [PDF]
, 2008 Collaboration with London design group Spin, with contributing essays by Russ Bestley and Malcolm Garrett, on the subject of punk graphic design.
Bestley, Russ
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