Results 71 to 80 of about 846,152 (303)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Geoglyphs of Titicaca as an ancient example of graphic design [PDF]
, 2010 arXiv, Cornell Univeristy ...
Sparavigna, Amelia Carolina
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
RIOT: a simple graphical assembly tool [PDF]
, 1982 Errors in the chip assembly process are harder to find than errors in cell design, since they belong to no specific part of the design, but rather to the assembly as a whole. Assembly errors are more costly than call design errors also, since they often
Rowson, Jim, Trimberger, Stephen
core
Medir la creatividad en diseño gráfico [PDF]
, 2013 En esta investigación se construye un marco conceptual donde se integra la creatividad y el diseño gráfico. Se introduce el modelo tridimensional de la creatividad en el diseño gráfico, en el que la creatividad es disertada en tres dimensiones, novedad ...
Ayala Pérez, José Luis
core +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Acta Chimica Slovenica, 2019 In the material extrusion of the thermoplastic filaments, known as Fused Deposition Modelling, usually, pure thermoplastic polymers are used. Recently, the focus of the research is given to the development of new biocomposite thermoplastic materials.
Diana Gregor-Svetec +4 more
doaj +1 more source
Producing Children\u27s Toys through 3-D Printing: A Multidisciplinary Approach [PDF]
, 2013 One of the things that first attracted me to VCU was the opportunity for interdisciplinary discussions and interactions. I saw HSURP as a way to push my boundaries and interact with peers from different disciplines.
Rifareal, Rebekah
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source