Results 71 to 80 of about 93,967 (257)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Angle-Dependent Glare Behavior in LED Luminaires: A Unified cosm Model for Urban Observers
OpticsGlare is a critical factor in the design of LED luminaires for street lighting, particularly in environments where pedestrians, cyclists and drivers coexist.
Juan de Dios Unión-Sánchez +3 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Ensuring Southern Spain’s Energy Future: A LEAP-Based Scenario for Meeting 2030 and 2050 Goals
Applied SciencesThe transition towards a low-carbon energy system remains a critical challenge for regions heavily dependent on fossil fuels, such as Andalusia. This study proposes an energy planning framework based on the Low Emissions Analysis Platform (LEAP) to model
Lucía Galán-Cano +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Journal of Architecture, Art & Humanistic Science, 2018 Recently, societies are exposed to many socio-economic and political changes that, in turn, affect the social component and psychological structures of individuals' structure, affecting the behavioral and moral and moral systems of society.
Abeer Al Desouki, Eman Hanafy
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Effects of Light Intensity on Tracing Digital Image into Vector Image
Journal of Architecture, Art & Humanistic Science, 2018 This paper aims to study the effects of light intensity on the digital image production, and therefore the accurate reproduction of details when tracing this digital image to the vector image.
Tarek Hamd Allah
doaj +1 more source
Retracted: Analysis of Graphic Design Based on AI Interaction Technology. [PDF]
J Environ Public Health, 2023 Environmental And Public Health JO.
europepmc +1 more source