Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Graphic Design 2018: A snapshot of 4-year undergraduate programs in the U.S. [PDF]
, 2022 Graphic design as a discipline is more complex than it might initially seem, and in many ways is still struggling to establish its independence from the fine arts as well as other disciplines within and outside of design.
Clarahan, Angela
core +1 more source
Homoclinic Solutions of Singular Nonautonomous Second-Order Differential Equations
Boundary Value Problems, 2009 This paper investigates the singular differential equation , having a singularity at . The existence of a strictly increasing solution (a homoclinic solution) satisfying , is proved provided that has two zeros and a linear behaviour near .
Rachůnková Irena +1 more
doaj
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Using digital storytelling as a methodology for the introduction of socially responsible graphic design in a University Bachelor of Computer Graphic Design Programme [PDF]
, 2009 This paper case studies the pedagogical methodology for a digital storytelling project involving final semester Bachelor of Computer Graphic Design students and students from a community based charitable arts trust. A young artist is paired with a senior
Vanderschantz, Nicholas
core
Uniqueness and Parameter Dependence of Positive Solution of Fourth-Order Nonhomogeneous BVPs
Boundary Value Problems, 2010 We investigate the following fourth-order four-point nonhomogeneous Sturm-Liouville boundary value problem: , , , where and are nonnegative parameters.
Sun Jian-Ping, Wang Xiao-Yun
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Global Existence, Uniqueness, and Asymptotic Behavior of Solution for
Journal of Inequalities and Applications, 2010 We study the global existence and uniqueness of a solution to an initial boundary value problem for the nonlinear wave equation with the -Laplacian operator . Further, the asymptotic behavior of solution is established.
Chen Caisheng, Yao Huaping, Shao Ling
doaj
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Linear Impulsive Periodic System with Time-Varying Generating Operators on Banach Space
Advances in Difference Equations, 2007 A class of the linear impulsive periodic system with time-varying generating operators on Banach space is considered. By constructing the impulsive evolution operator, the existence of -periodic -mild solution for homogeneous linear impulsive periodic ...
Wei W, Wang JinRong, Xiang X
doaj