Results 51 to 60 of about 7,119,691 (324)

GRAPHICAL AND ANALYTICAL APPROACH ON CYLINDRICAL – CONICAL INTERSECTIONS

open access: yesJournal of Industrial Design and Engineering Graphics, 2019
The cylindrical – conical intersections are often met in technique as parts of pipes, tanks, bends etc. The paper work proposes a comparison between methods to solve the cylindrical – conical intersection problems.
Vanda - Ligia Danaila   +1 more
doaj   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

VCF observer: a user-friendly software tool for preliminary VCF file analysis and comparison

open access: yesBMC Bioinformatics
Background Advancements over the past decade in DNA sequencing technology and computing power have created the potential to revolutionize medicine. There has been a marked increase in genetic data available, allowing for the advancement of areas such as ...
Abdullah Asım Emül   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Understanding human functioning using graphical models

open access: yesBMC Medical Research Methodology, 2010
Background Functioning and disability are universal human experiences. However, our current understanding of functioning from a comprehensive perspective is limited.
Maathuis Marloes H   +6 more
doaj   +1 more source

Evaluation of Lightning Impulse Test by Frequency Response Analysis [PDF]

open access: yes, 2006
In this work are presented the basis for improving the interpretation of transformer lightning impulse test and the development of a graphical user interface system, which allows comparisons of time domain data and frequency response.
Ramírez, Jorge, Valecillos, Baudilio
core   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

High-Dimensional Sparse Graph Estimation by Integrating DTW-D Into Bayesian Gaussian Graphical Models

open access: yesIEEE Access, 2018
Graphical models provide an effective way to reveal complicated associations in data and especially to learn the structures among large numbers of variables with respect to few observations in a high-dimensional space.
Ying Li, Xiaojun Xu, Jianbo Li
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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