Results 141 to 150 of about 12,459,066 (303)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
A 3D GRAPHICAL MODELLING METHOD FOR HUMAN FEMUR BONE
Journal of Industrial Design and Engineering Graphics, 2006 The paper presents a method of study and the steps to obtain a virtual bone. For that purpose was used a CAD parametric software which permits to define models with a high degree of difficulty.
POPA Dragoş +3 more
doaj
Graphical Method for Choosing Optimized Conditions Given a Pump Pressure and a Particle Diameter in Liquid Chromatography. [PDF]
Anal Chem, 2016 Groskreutz SR, Weber SG.
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
NITELIGHT: A Graphical Tool for Semantic Query Construction
, 2008 Query formulation is a key aspect of information retrieval, contributing to both the efficiency and usability of many semantic applications. A number of query languages, such as SPARQL, have been developed for the Semantic Web; however, there are, as yet,
Smart, Paul R. +3 more
core +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Design of Paper Picking Mechanism in Printing Quality Inspection Machine
Jixie chuandong, 2018 The packaging carton papers of products need to be checked by quality control machine after printing. Thus,a stack of carton papers shall be taken out one by one and placed onto conveyor belt. A paper picking mechanism composed of two cams and five links（
Gao Xuyao, Zhang Chun, Liang Jinsheng
doaj
The graphical method for goodness of fit test in the inverse Weibull distribution based on multiply type-II censored samples. [PDF]
Springerplus, 2015 Kang SB, Han JT.
europepmc +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source