Results 51 to 60 of about 397,680 (259)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

HLYWD: a program for post-processing data files to generate selected plots or time-lapse graphics [PDF]

, 1980
The program HLYWD is a post-processor of output files generated by large plasma simulation computations or of data files containing a time sequence of plasma diagnostics. It is intended to be used in a production mode for either type of application; i.e., it allows one to generate along with the graphics sequence, segments containing title, credits to ...
openaire   +2 more sources

PSNtools for standalone and web-based structure network analyses of conformational ensembles

Computational and Structural Biotechnology Journal, 2022
Structure graphs, in which interacting amino acids/nucleotides correspond to linked nodes, represent cutting-edge tools to investigate macromolecular function.The graph-based approach defined as Protein Structure Network (PSN) was initially implemented ...
Angelo Felline, Michele Seeber, Francesca Fanelli   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A finite-element toolbox for the stationary Gross-Pitaevskii equation with rotation

, 2016
We present a new numerical system using classical finite elements with mesh adaptivity for computing stationary solutions of the Gross-Pitaevskii equation.
Auliac, Sylvain, Danaila, Ionut, Hecht, Frédéric, Vergez, Guillaume   +3 more
core   +1 more source

Analysis of post-mining excavations as places for municipal waste

E3S Web of Conferences, 2018
Waste management planning is an interdisciplinary task covering a wide range of issues including costs, legal requirements, spatial planning, environmental protection, geography, demographics, and techniques used in collecting, transporting, processing ...
Górniak-Zimroz Justyna
doaj   +1 more source

SIMPLE 3.0. Stream single-particle cryo-EM analysis in real time

Journal of Structural Biology: X, 2020
We here introduce the third major release of the SIMPLE (Single-particle IMage Processing Linux Engine) open-source software package for analysis of cryogenic transmission electron microscopy (cryo-EM) movies of single-particles (Single-Particle Analysis,
Joseph Caesar, Cyril F. Reboul, Chiara Machello, Simon Kiesewetter, Molly L. Tang, Justin C. Deme, Steven Johnson, Dominika Elmlund, Susan M. Lea, Hans Elmlund   +9 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

RUMD: A general purpose molecular dynamics package optimized to utilize GPU hardware down to a few thousand particles

SciPost Physics, 2017
RUMD is a general purpose, high-performance molecular dynamics (MD) simulation package running on graphical processing units (GPU's). RUMD addresses the challenge of utilizing the many-core nature of modern GPU hardware when simulating small to medium
Nicholas P. Bailey, Trond S. Ingebrigtsen, Jesper Schmidt Hansen, Arno A. Veldhorst, Lasse Bøhling, Claire A. Lemarchand, Andreas E. Olsen, Andreas K. Bacher, Lorenzo Costigliola, Ulf R. Pedersen, Heine Larsen, Jeppe C. Dyre, Thomas B. Schrøder
doaj   +1 more source

Extension of the NEAMS workbench to parallel sensitivity and uncertainty analysis of thermal hydraulic parameters using Dakota and Nek5000

Nuclear Engineering and Technology, 2021
With the increasing availability of high-performance computing (HPC) platforms, uncertainty quantification (UQ) and sensitivity analyses (SA) can be efficiently leveraged to optimize design parameters of complex engineering problems using modeling and ...
Marc-Olivier G. Delchini, Laura P. Swiler, Robert A. Lefebvre   +2 more
doaj   +1 more source