Results 41 to 50 of about 303,097 (314)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Личность художника в зеркале творчества

open access: yesИскусство Евразии, 2020
В статье сделан обзор выставки Михаил Верхоланцев. Ксилографии в Ирбитском государственном музее изобразительных искусств. В составе ретроспективной экспозиции 132 гравюры, созданные в период с 1970 по 2018 год.
Оськина, Ирина Николаевна
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Functions and performance of the Basics and Applications of Computer Graphics and Graphic Design

open access: yesKonya Sanat, 2022
This paper focuses on the basics and applications of computer graphics and why it is important for students to be abreast of the nitty-gritty of this area of study and by extension, knowing why the study of computer graphics is of immense importance ...
Felix Osaigbovo
doaj   +1 more source

Computer Graphics in Europe

open access: yes, 2022
S.62-63European research covers the whole spectrum of computer graphics topics. This enabling technology, based on modern information technology, is considered key for the future development of the European economy.1 Here is a brief overview of some ...
Encarnação, José L.
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

plotROC: A Tool for Plotting ROC Curves

open access: yesJournal of Statistical Software, 2017
Plots of the receiver operating characteristic (ROC) curve are ubiquitous in medical research. Designed to simultaneously display the operating characteristics at every possible value of a continuous diagnostic test, ROC curves are used in oncology to ...
Michael C. Sachs
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A graphical calculus

open access: yes, 1995
We present a graphical calculus, which allows mathematical formulae to be represented and reasoned about using a visual representation. We define how a formula may be represented by a graph, and present a number of laws for transforming graphs, and describe the effects these transformations have on the corresponding formulae.
Curtis, S, Lowe, G
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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