Results 111 to 120 of about 2,686,069 (331)
, 2019 We study the number of connected graphs with $n$ vertices that cannot be written as the cartesian product of two graphs with fewer vertices. We give an upper bound which implies that for large $n$ almost all graphs are both connected and cartesian prime.
Aldi, Marco
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
European Journal of Combinatorics, 2000 Let \(G= (V,E)\) be a finite simple graph with \(n\geq 2\) vertices. \(G\) is called a concordance graph if the number of its induced three-vertex one-edged subgraphs equals the number of its induced three-vertex two-edged subgraphs, the class of these graphs be denoted by \({\mathfrak C}\).
Fishburn, Peter, Monjardet, Bernard
openaire +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Computer Science Journal of Moldova, 2015 We study some properties of minimum convex covers and minimum convex partitions of simple graphs. We establish existence of graphs with fixed number of minimum convex covers and minimum convex partitions.
Radu Buzatu, Sergiu Cataranciuc
doaj
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Routing in Unidirectional (n,k)-star graphs [PDF]
Journal of Systemics, Cybernetics and Informatics, 2006 The class of (n,k)-star graphs and their unidirectional version were introduced as generalizations of star graphs and unidirectional star graphs respectively.
Eddie Cheng, Serge Kruk
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source