Results 201 to 210 of about 926,750 (319)

The Minimal Spectral Radius of Graphs with a Given Diameter

AMS classsifications: 05C50; 05E99; 94C15;graphs;spectral radius;diameter;networks;virus ...
Kooij, R.E., Dam, E.R. van
core  

Optimizing large-scale graph database ingestion through edge value ranking: a proposed framework. [PDF]

Front Big Data
Madduru PR, Thomas B.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Explaining hidden mechanisms: a generative model for causal graphs with nonlinear latent factors. [PDF]

Front Artif Intell
Maruhashi K, Park H, Yamaguchi R, Miyano S.   +3 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Probing the Hall anomaly and electronic structure in kagome metal RbV₃Sb₅ under hydrostatic pressure. [PDF]

Sci Technol Adv Mater
Poon TF, Wang Z, Wang L, Tsui YK, Zhou Z, Wang W, Tsang CW, Pourret A, Seyfarth G, Knebel G, Goh SK.   +10 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Curvature on Graphs with Negative Edge Weights. [PDF]

IEEE Trans Netw Sci Eng
Grange D, Sun Y, Weistuch C, Elkin R, Phillips S, Deasy JO, Georgiou T.   +6 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Rhaponticin alleviates pancreatic acinar cell necrosis by attenuating oxidative stress via modulation of the HIF-1α signaling pathway. [PDF]

Redox Rep
Xie X, Yang P, Wang S, Xu X, Wang L, Li P, Lu G, Chen W, Sun R, Zhang J, Wang Z.   +10 more
europepmc   +1 more source