Results 51 to 60 of about 291,095 (291)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine +14 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Fast and accurate edge orientation processing during object manipulation
eLife, 2018 Quickly and accurately extracting information about a touched object’s orientation is a critical aspect of dexterous object manipulation. However, the speed and acuity of tactile edge orientation processing with respect to the fingertips as reported in ...
J Andrew Pruszynski +2 more
doaj +1 more source
Chained activation of the motor system during language understanding [PDF]
, 2017 Two experiments were carried out to investigate whether and how one important characteristic of the motor system, that is its goal-directed organization in motor chains, is reflected in language processing. This possibility stems from the embodied theory
Borghi, ANNA MARIA +3 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Natural Virtual Reality User Interface to Define Assembly Sequences for Digital Human Models
Applied System Innovation, 2020 Digital human models (DHMs) are virtual representations of human beings. They are used to conduct, among other things, ergonomic assessments in factory layout planning.
Andreas Geiger +2 more
doaj +1 more source
A Method for Measuring Contact Points in Human–Object Interaction Utilizing Infrared Cameras
Frontiers in Robotics and AI, 2022 This article presents a novel method for measuring contact points in human–object interaction. Research in multiple prehension-related fields, e.g., action planning, affordance, motor function, ergonomics, and robotic grasping, benefits from accurate and
Jussi Hakala, Jukka Häkkinen
doaj +1 more source
Visual adaptation to goal-directed hand actions [PDF]
, 2004 Prolonged exposure to visual stimuli, or adaptation, often results in an adaptation “aftereffect” which can profoundly distort our perception of subsequent visual stimuli.
Abelson +92 more
core +3 more sources
Psychonomic Bulletin & Review, 2006 Despite the great amount of research that has been done regarding the time it takes to move the hand to targets of varying distances and widths, it is unclear whether target distance and width are both represented in movement plans prior to movement initiation. We addressed this question by studying performance in an object manipulation task.
David A, Rosenbaum +2 more
openaire +2 more sources