Results 251 to 260 of about 364,671 (298)

XPC Deficiency Activate Cisplatin‐Mediated Autophagy in Bladder Cancer by Limiting Novel PHRF1‐Mediated Ubiquitination of the p53 Protein

open access: yesAdvanced Science, EarlyView.
This study reveals that XPC regulates autophagy signaling beyond its noncanonical DNA repair role, uncovering the XPC‐p‐ATM‐KDM4A‐PHRF1 axis as a novel mechanism for autophagy modulation under DNA damage stress. It identifies PHRF1 as a novel p53 ubiquitin ligase.
Baixiong Zhao   +10 more
wiley   +1 more source

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

open access: yesAdvanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song   +9 more
wiley   +1 more source

Cortical Microvascular Pulsatility in the Aging Mouse Brain and the Confounding Effects of Anesthesia

open access: yesAdvanced Science, EarlyView.
Multi‐modal optical imaging reveals microvascular pulsatility in the brain cortex of awake and anaesthetized mice. Awake hemodynamics in male mice are found to be remarkably stable until late life, with flow pulsatility being significantly higher than in females, despite similar average perfusion.
Mia Viuf Skøtt   +5 more
wiley   +1 more source

Non‐Tariff Measures and U.S. Agricultural Exports

open access: yesApplied Economic Perspectives and Policy, EarlyView.
Abstract How much do non‐tariff measures (NTMs) affect U.S. agricultural exports? While countries maintain a large and diverse set of NTMs to safeguard the health of plants, animals, and humans, policymakers and regulatory bodies may neglect the impact these measures have on international trade.
Yunus Emre Karagulle   +2 more
wiley   +1 more source

A Long Term Follow-up Study of Patients with Graves' Disease : The Correlation between Thyroid Functions and Histological Findings

open access: diamond, 1982
Yoshihiko Hirota   +8 more
openalex   +2 more sources

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