Results 91 to 100 of about 9,613,246 (402)

Effects of Radioiodine Therapy on the Natural History of Graves' Ophtalmopathy

Клиническая и экспериментальная тиреоидология, 2007
21 patients with Graves’ disease and Graves’ ophthalmopathy (GO) received radioiodine treatment (RIT). Before 131-I therapy in all patients GO were non-active and no severe.

doaj   +1 more source

Candidate gene associations reveal sex‐specific Graves’ disease risk alleles among Chinese Han populations

Molecular Genetics & Genomic Medicine, 2020
Background With several susceptibility single nucleotide polymorphisms identified by case–control association studies, Graves’ disease is one of the most common forms of autoimmune thyroid disease.
Chen‐Yan Yan, Yu‐Ru Ma, Feng Sun, Rui‐Jia Zhang, Ya Fang, Qian‐Yue Zhang, Feng‐Yao Wu, Shuang‐Xia Zhao, Huai‐Dong Song   +8 more
doaj   +1 more source

Особенности гуморального антиэндотоксинового иммунитета у больных диффузным токсическим зобом в зависимости от длительности заболевания [PDF]

, 2009
В основi патогенезу дифузного токсичного зобу (ДТЗ) лежать аутоiмуннi механiзми. Одним з важливих чинникв, здатних призводити до формування таких порушень при ДТЗ, може бути патологічна дiя ендотоксину (ЕТ) грамнегативноi флори кишечнику.
Бакова, А.А., Белоглазов, В.А., Гордиенко, А.И., Кулагина, Ю.Ю.   +3 more
core  

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Association between thymic hyperplasia and serum calcium level in Graves’ disease

BMC Endocrine Disorders
Background Graves' disease increases bone resorption in hyperthyroidism, leading to elevated serum calcium levels and a negative bone balance. Thymic hyperplasia is observed in some Graves' disease patients.
Jing Zeng, Lan Li, Dong Wei
doaj   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

Transient neonatal hyperthyroidism [PDF]

, 2014
Graves’ disease is the main cause of hyperthyroidism in women of childbearing age. It occurs by the presence of serum immunoglobulins which stimulate the thyrotropin receptor (TRAbs) and may cross the placenta.
Dias, A, Dinis, I, Faria, D, Jerónimo, M, Mimoso, G, Mirante, A, Moinho, R, Nunes-Vicente, I, Oliveira, A   +8 more
core  

Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]

, 2013
Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher, Solomon, Daniel, Sosa, Julie Ann, Tuggle, Charles   +3 more
core   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source