Results 181 to 190 of about 11,494 (215)

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Ecological sports tourism based on multi population evolutionary algorithm and entrepreneurship environment for sustainable development. [PDF]

Sci Rep
Hu B, Zhang Y.
europepmc   +1 more source

An Embodied Paper‐Based Microfluidic Al‐Air Battery for Enduring Untethered Insect‐Scale Robots

Advanced Science, EarlyView.
This work presents a centimeter‐scale microfluidic aluminum–air battery (MFAAB) with dual‐surface anode and F−‐mediated byproduct decomposition. The design enables a high capacity of 2697.05 mAh/g Al and delivers tens of milliwatts to power LEDs, motors, and a toy car.
Yun Yang, Tao Jiang, Zhongyue Lu, Dapeng Fan, Zucheng Yi, Zirong Luo   +5 more
wiley   +1 more source

Emotional Needs in the Face of Climate Change and Barriers for Pro-Environmental Behaviour in Dutch Young Adults: A Qualitative Exploration. [PDF]

Int J Environ Res Public Health
Venhof VSM, Jeronimus BF.
europepmc   +1 more source

A Data‐Driven Inverse Design Methodology for Magnetic Soft Millirobots Navigating in Confined Spaces

Advanced Science, EarlyView.
A data‐efficient inverse design framework automates the optimization of magnetic soft millirobots for confined‐space navigation. Integrating a physics‐based Cosserat rod model with Bayesian optimization efficiently identifies high‐performance geometries.
Ziyu Ren, Hong Wang, Chak Wang Tse, Yi Zheng, Xi Chen, Wenqi Hu   +5 more
wiley   +1 more source

Emotional and attentional anomalies underlying triarchic psychopathic traits: an EEG-startle blink study. [PDF]

BMC Psychol
Soong TF, Booij JPA, Stapel K, Bunnik C, Zwilling I, Karp A, Koekkoek SKE, Gultig KD, Roggeveen LEM, Boele CP, De Zeeuw CI, Boele HJ, van Dongen JDM.   +12 more
europepmc   +1 more source

Mixing‐Driven Defects and Composition Evolution in Multi‐Material Metal Additive Manufacturing

Advanced Science, EarlyView.
Operando synchrotron X‐ray imaging coupled with high‐fidelity multiphysics modeling uncovers how inter‐material mixing reshapes keyhole dynamics and drives distinct pore‐formation pathways in multi‐material laser powder bed fusion (LPBF). Composition‐dependent instabilities trigger defects, whereas rescanning suppresses porosity and homogenizes Cu ...
Zhilang Zhang, Steve Gaudez, Mario Togni, Steven Van Petegem, Markus Bambach, Mamzi Afrasiabi   +5 more
wiley   +1 more source

The Hyperbolically Symmetric Black Hole. [PDF]

Entropy (Basel)
Herrera L, Witten L.
europepmc   +1 more source

Architecture-Encoded Degradation Kinetics and Pathways through the Shape and Size of Polymeric Vesicles. [PDF]

J Am Chem Soc
Wang D, Luan J, White PB, Wilson DA.
europepmc   +1 more source

Sociability and whole-brain resting-state connectivity. [PDF]

Sci Rep
Rovný M, Sprooten E, Ilioska I, Fanelli G, Marquand AF, Fabbri C, Kas MJH, Serretti A, Franke B.   +8 more
europepmc   +1 more source