Results 51 to 60 of about 481,795 (316)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Spacetime and the Philosophical Challenge of Quantum Gravity [PDF]

open access: yes, 2001
We survey some philosophical aspects of the search for a quantum theory of gravity, emphasising how quantum gravity throws into doubt the treatment of spacetime common to the two `ingredient theories' (quantum theory and general relativity), as a 4 ...
Butterfield, Jeremy   +3 more
core   +1 more source

Decaying gravity [PDF]

open access: yesPhysical Review D, 2006
We consider the possibility of energy being exchanged between the scalar and matter fields in scalar-tensor theories of gravity. Such an exchange provides a new mechanism which can drive variations in the gravitational 'constant' G. We find exact solutions for the evolution of spatially flat Friedman-Roberston-Walker cosmologies in this scenario and ...
Clifton, T, Barrow, JD
openaire   +3 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

The philosophy behind quantum gravity [PDF]

open access: yes, 2006
This paper investigates some of the philosophical and conceptual issues raised by the search for a quantum theory of gravity. It is critically discussed whether such a theory is necessary in the first place, and how much would be accomplished if it is ...
Zinkernagel, Henrik   +2 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

2D transverse laser cooling of a hexapole focused beam of cold BaF molecules

open access: yesCommunications Physics
Laser cooling of molecules is a powerful technique for producing cold, slow beams for precision measurements and quantum control, yet its implementation remains challenging due to molecular complexity.
J. W. F. van Hofslot   +21 more
doaj   +1 more source

Quasicrystalline spin foam with matter: definitions and examples

open access: yesAcademia Quantum
In this work, we define quasicrystalline spin networks as a subspace within the standard Hilbert space of loop quantum gravity, effectively constraining the states to coherent states that align with quasicrystal geometry structures.
Marcelo Maciel Amaral   +2 more
doaj   +1 more source

The information metric on the moduli space of instantons with global symmetries

open access: yesPhysics Letters B, 2016
In this note we revisit Hitchin's prescription [1] of the Fisher metric as a natural measure on the moduli space of instantons that encodes the space–time symmetries of a classical field theory. Motivated by the idea of the moduli space of supersymmetric
Emanuel Malek   +2 more
doaj   +1 more source

The Log of Gravity [PDF]

open access: yesThe Review of Economics and Statistics, 2003
AbstractAlthough economists have long been aware of Jensen's inequality, many econometric applications have neglected an important implication of it: under heteroskedasticity, the parameters of log-linearized models estimated by OLS lead to biased estimates of the true elasticities.
Santos Silva, Joao M C   +1 more
openaire   +6 more sources

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