Results 111 to 120 of about 16,583,366 (283)

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

open access: yesAdvanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang   +12 more
wiley   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

open access: yesAdvanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li   +8 more
wiley   +1 more source

Quantitative Evaluation of the Effectiveness of Chemical Peelings in Reducing Acne Lesions Based on Gray-Level Co-Occurrence Matrix (GLCM). [PDF]

open access: yesClin Cosmet Investig Dermatol, 2022
Odrzywołek W   +5 more
europepmc   +1 more source

RETRACTED: Touchless palm print recognition system design using Gray Level Co-occurrence Matrix feature with K-Nearest Neighbor classification in MATLAB [PDF]

open access: yes
The article with the title:  Touchless palm print recognition system design using Gray Level Co-occurrence Matrix feature with K-Nearest Neighbor classification in MATLAB has been retracted at the request of the Editor-in-Chief.
Silalahi, Lukman Medriavin   +2 more
core   +2 more sources

The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells

open access: yesAdvanced Science, EarlyView.
Purely geometric 3D Voronoi models predict the organisation of epithelial shells. The interplay of curvature, geometry, and topology enriches the number of pentagons in shells with lower number of cells. Small MDCK cysts and Mouse embryos match the top polygonal configurations in a compactness‐based ranking derived from the Voronoi model. In conclusion,
Laura Morato   +9 more
wiley   +1 more source

Application of Haralick texture features in brain [18F]-florbetapir positron emission tomography without reference region normalization

open access: yesClinical Interventions in Aging, 2017
Desmond L Campbell,1 Hakmook Kang,2 Sepideh Shokouhi1 On behalf of The Alzheimer’s Disease Neuroimaging Initiative 1Department of Radiology and Radiological Sciences, 2Department of Biostatistics, Vanderbilt University Medical Center ...
Campbell DL, Kang H, Shokouhi S
doaj  

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

open access: yesAdvanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang   +14 more
wiley   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

open access: yesAdvanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu   +11 more
wiley   +1 more source

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