Results 71 to 80 of about 38,903 (283)

Multi‐omic profiling reveals immune cell priming signature linked to lupus prognosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is a multi‐organ disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith   +23 more
wiley   +1 more source

Single‐cell level characterization of B cell depletion and repopulation following rituximab in systemic lupus erythematosus

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang   +9 more
wiley   +1 more source

Unlocking the “Virtual Cage” of Wildlife Surveillance [PDF]

open access: yes, 2017
The electronic surveillance of wildlife has grown more extensive than ever. For instance, thousands of wolves wear collars transmitting signals to wildlife biologists. Some collars inject wolves with tranquilizers that allow for their immediate capture
Lininger, Henry, Lininger, Tom
core   +1 more source

The impacts of biological invasions

open access: yesBiological Reviews, EarlyView.
ABSTRACT The Anthropocene is characterised by a continuous human‐mediated reshuffling of the distributions of species globally. Both intentional and unintentional introductions have resulted in numerous species being translocated beyond their native ranges, often leading to their establishment and subsequent spread – a process referred to as biological
Phillip J. Haubrock   +42 more
wiley   +1 more source

Gray wolf harvest in Idaho

open access: yesWildlife Society Bulletin, 2016
Regulated harvest is a relatively new phenomenon for gray wolves (Canis lupus) in the contiguous United States. Most studies of wolf harvest have been conducted in northern latitudes where wolf populations are large and human densities are low.
David E. Ausband
doaj   +1 more source

Experimentally derived δ¹³C and δ¹⁵N discrimination factors for gray wolves and the impact of prior information in Bayesian mixing models. [PDF]

open access: yesPLoS ONE, 2015
Stable isotope analysis of diet has become a common tool in conservation research. However, the multiple sources of uncertainty inherent in this analysis framework involve consequences that have not been thoroughly addressed.
Jonathan J Derbridge   +6 more
doaj   +1 more source

Classifying avian drinking behaviour: ecological insights and implications in a changing world

open access: yesBiological Reviews, EarlyView.
ABSTRACT Water is a fundamental currency of life, and its availability significantly influences animal behaviour, physiology and distributions. However, our knowledge around the dependence on water for drinking and the direct and indirect mechanisms driving related behaviours remains partial in the context of changing climates. Here, we review patterns
Shannon R. Conradie, Marc T. Freeman
wiley   +1 more source

Scavenging patterns of an inbred wolf population in a landscape with a pulse of human‐provided carrion

open access: yesEcology and Evolution, 2023
Scavenging is an important part of food acquisition for many carnivore species that switch between scavenging and predation. In landscapes with anthropogenic impact, humans provide food that scavenging species can utilize.
Camilla Wikenros   +9 more
doaj   +1 more source

What next? Rewilding as a radical future for the British countryside [PDF]

open access: yes, 2015
Rewilding is an optimistic environmental agenda to reverse the loss of biodiversity and reconnect society with nature. This chapter explores Britain’s ecological history, back to the Last Interglacial before the arrival of modern humans, when the climate
Macdonald, David W   +1 more
core   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

open access: yesCytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius   +6 more
wiley   +1 more source

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