Results 251 to 260 of about 1,764,326 (320)

Mode‐dependent Far‐field Radiation of Circularly Polarized Light by a Single Plasmonic Nanohelix

open access: yesAdvanced Optical Materials, Volume 13, Issue 8, March 13, 2025.
The numerical simulations explored the chiroptical response and far‐field radiation behaviors of single plasmonic nanoantennas transitioning into helical structures. This study highlights the ability of these plasmonic nanohelices to regulate the far‐field directionality of radiation power and circular polarization in plasmon‐exciton coupled systems ...
Yiou Cui   +10 more
wiley   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun   +17 more
wiley   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

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