Results 51 to 60 of about 1,764,326 (320)

The 1967 Patent Law Debate—First-to-Invent vs. First-to-File [PDF]

open access: yes, 1967
United States patent law has traditionally been based on the proposition that the first inventor, not the first person to file a patent application, is the only person entitled to a patent. Nevertheless, the President\u27s Commission on the Patent System
Frost, George E.
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Arts for All: 6 Year Review [PDF]

open access: yes, 2008
In September 2002, the Los Angeles County Board of Supervisors adopted Arts for All: Los Angeles County Regional Blueprint for Arts Education, a strategic plan to restore arts education -- in dance, music, theatre, and the visual arts -- to the 1.7 ...

core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The great cultural divide [PDF]

open access: yes, 2008
In recent years, Roger Williams University has experienced a great deal of debate regarding some of the most controversial political and cultural issues that are confronting contemporary America society.
Fournier, Eric
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The friendship of Matthew and Paul: A response to a recent trend in the interpretation of Matthew’s Gospel

open access: yesHTS Teologiese Studies/Theological Studies, 2009
David Sim has argued that Matthew’s so-called Great Commission (Mt 28:16–20) represents a direct anti-Pauline polemic. While this thesis may be theoretically possible and perhaps fi ts within the perspective of an earlier era in New Testament research ...
Joel Willitts
doaj   +1 more source

Protecting Shoreland and Riparian Buffers Workshop (2007) [PDF]

open access: yes, 2008
The New Hampshire Estuaries Project (NHEP) organized and implemented a workshop on protecting shoreland and riparian buffers. A number of other organizations, including three regional planning commissions, NH Fish and Game Department, NH Department of ...
Hunter, Jennifer
core   +1 more source

Home - About - Disclaimer - Privacy