Results 21 to 30 of about 83,566 (261)

EX-YU prostor u epohi globalnog geopolitičkog preoblikovanja // EX-YU space in the era of Global Geopolitical Transformation [PDF]

open access: yesHistorijski pogledi
The area of the Balkan Peninsula has been a zone of conflicting geopolitical interests for centuries. For centuries, influences from the West, East, North and South have shaped this area.
Radenko Šćekić, Ljubomir Popović
doaj   +1 more source

Navigating Power Dynamics: Middle Powers and their Role in Asia-Pacific Rivalry

open access: yesBTTN Journal
Great power rivalry between China and US has focused on the Asia-Pacific area because of its dynamic geopolitical and economic environment. In light of best-known theories liberalism, constructivism and realism, this article examines role of middle ...
Shahram Iqbal, Muhammad Arif Khan
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Geopolitical competition of great powers in the Arctic

open access: yesУправление
The article examines the complex issues of Arctic security arising from changing geopolitical realities; explores the new Cold War atmosphere in the region mixed with melting ice, which affects military planning and opens new economic opportunities and ...
E. S. Karsanova
doaj   +1 more source

Energetic diplomacy and its role on creation of a new multipolar world

open access: yesAcademicus International Scientific Journal, 2016
International correlations through the last years have been remarked as dramatic in character, and very often followed through with unpredictable events, such as the Arab spring, chronic and confessional wars raging through the Middle east, than the ...
Igor Gelev, Muhamet Racaj
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The “Balkan Tea Party” of the Great Powers

open access: yesVestnik MGIMO-Universiteta
Book Review: Ponomareva E., Arlyapova E. 2024. The Western Balkans in the run-up to and during the current crisis: players and figures. Moscow: Prospekt Publishing House. 318 p. (in Russian)
V. A. Avatkov
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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