Results 91 to 100 of about 2,753,312 (286)

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

Net Fiscal Stimulus During the Great Recession [PDF]

This paper studies the patterns of fiscal stimuli in the OECD countries propagated by the global crisis. Overall, we find that the USA net fiscal stimulus was modest relative to peers, despite it being the epicenter of the crisis, and having access to ...
Gurnain Kaur Pasricha, Joshua Aizenman
core  

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Rent growth near rail stations after the Great Recession

Journal of Sustainable Real Estate
This study provides an incisive analysis of U.S. rail station area rent trends from 2012 to 2016, post-Great Recession. Utilizing Ordinary Least Squares (OLS), Hierarchical Spatial Autoregressive (HSAR), and Geographically Weighted Regression (GWR ...
John L. Renne, Jyothi Chava, Bruce Appleyard, Tara Tolford   +3 more
doaj   +1 more source

The labor market in the Great Recession [PDF]

This paper documents the adjustment of the labor market during the recession, and places it in the broader context of previous postwar downturns. What emerges is a picture of labor market dynamics with three key recurring themes: 1.
Aysegül Sahin, Michael Elsby, Bart Hobjin   +2 more
core  

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

The Effect of the 2008 Recession on Gifted Education Funding Across the State of Texas

AERA Open, 2018
The effect of the 2008 Recession has reverberated throughout public education in the United States. This paper examines how the gifted education funding in the state of Texas changed following the Great Recession.
Jaret Hodges, Juliana Tay, Ophélie Desmet, Emine Ozturk, Nielsen Pereira   +4 more
doaj   +1 more source

Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues

Advanced Science, EarlyView.
Defined biological and physical quality thresholds achieved through acoustic manipulation regulate cellular alignment and spatial organization, promoting self‐assembling vasculature, extracellular matrix deposition, and angiogenic responses, thereby establishing critical acoustic patterning requirements for engineered vascular tissue development in ...
Oscar O'Dwyer Lancaster‐Jones, Russell Quinn, Niloofar Khoshdel Rad, Kilian Paul, Andrea Frank, Daniela F. Duarte Campos   +5 more
wiley   +1 more source

2008 Krizi ve İşsizliğe Etkisi Üzerine Bir Uygulama: N-11 Ülkeleri

Ekonomi, Politika & Finans Araştırmaları Dergisi, 2018
Küresel finansal kriz tüm dünya ekonomilerini olumsuz etkilemiştir. 2008’de meydana gelen küresel finansal kriz nedeniyle sadece ekonomik sistem olumsuz etkilenmemiş, aynı zamanda sosyal ve kültürel hayatta da son derece yıkıcı etkiler oluştuğu ...
Tuğba Koyuncu
doaj   +1 more source