Results 161 to 170 of about 318,662 (338)

In Situ Engineering of Tumor Cells as Self‐Sustaining cDC1 Programming Factories for Effective Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The fused EV platform AS16‐EL@MPLA/p‐FX reprograms tumor cells into cytokine‐producing factories that continuously secrete XCL1 and FLT3L to recruit and differentiate cDC1s, while embedded MPLA activates them through TLR4 signaling and AS16 prevents their exhaustion, thereby enhancing antitumor immunity and establishing durable immune memory against ...
Shuiling Jin   +16 more
wiley   +1 more source

Champaign County: Snapshot of Poverty, Income, and Health Insurance Coverage [PDF]

open access: yes, 2011
The newly released data from the U.S. Census Bureau's American Community Survey provide a glimpse of the ongoing impacts of the Great Recession for millions of individuals and families. This snapshot of your community's data includes a comparison of 2010

core  

Dynamic Fibrous Hydrogels for Stem Cell Homing and In Situ Bone Regeneration

open access: yesAdvanced Science, EarlyView.
A dynamic fibrous hydrogel (DFH) is developed by covalent crosslinking of gelatin with tea‐derived trichomes, which integrates the structural and compositional fidelity of native extracellular matrix with photothermal and oxidative responsiveness, introducing a novel “stem cell recruits stem cell” strategy that orchestrates co‐homing of endogenous and ...
Jianmei Chen   +7 more
wiley   +1 more source

Employment Polarization and Job Quality in the Crisis [PDF]

open access: yes, 2013
[Excerpt] European labour markets added nearly 30 million new jobs in a golden age of employment creation prior to the onset of the Great Recession in 2008. The markets have subsequently shed five million jobs and unemployment – rising rapidly once again
Fernandez-Macias, Enriqued   +2 more
core   +1 more source

PLA2G16‐Mediated Tetracosatetraenoic Acid Rewires Fatty Acid Oxidation to Impair CD8+ T Cell Immune Function in Promoting Breast Cancer Lung Metastasis

open access: yesAdvanced Science, EarlyView.
Illustrating how tumor‐derived PLA2G16 regulates tetracosatetraenoic acid (C24:4 (n‐6)) accumulation and CD8+ T cell activation via the C24:4‐PPARα‐FAO axis in early metastatic niches, thereby promoting lung metastasis of triple‐negative breast cancer.
Yubi Gan   +13 more
wiley   +1 more source

Credit flows to businesses during the Great Recession [PDF]

open access: yes
During the last recession, credit flows suffered their worst slowdown since World War II. A look at selected credit market measures gives some insight into why the slowdown was so severe.
Pedro Amaral
core  

Southeastern Kentuckians remain optimistic through Great Recession: growing concerns about sprawl, housing, and recreational opportunities [PDF]

open access: yes, 2011
In May and June of 2007, Carsey Institute researchers surveyed 1,000 randomly selected respondents from Kentucky’s Harlan and Letcher counties, and between November 2010 and January 2011, they returned to survey 1,020 different randomly selected ...
Ulrich, Jessica D.
core   +1 more source

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