Results 191 to 200 of about 318,662 (338)

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Polarization‐Multiplexed Metalens Enables Switchable and Compact Chromatic Confocal Sensing with Dual‐Mode Precision Control

open access: yesAdvanced Science, EarlyView.
This work breaks conventional design paradigms by leveraging a polarization‐multiplexed metasurface to create the first chromatic confocal sensor with dynamically switchable measurement performance, achieving 10‐fold miniaturization (Ø1 mm vs cm‐scale conventional probes).
Zhicheng Zhao   +5 more
wiley   +1 more source

The Great Recession and Material Hardship [PDF]

open access: yes
Little research looks at the relationship between macroeconomic indicators and material hardship. High unemployment rates as a result of economic downturns are likely to lead to lost income, increased poverty, and material hardship. We examine the effect
Irwin Garfinkel   +2 more
core  

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