Results 41 to 50 of about 318,662 (338)

Couples' paid work, state-level unemployment, and first births in the United States

open access: yesDemographic Research, 2021
Background: While most studies analyze male's and female's employment separately, this study adopts a couple-level approach to relate paid work to childbearing in the United States.
Chiara Ludovica Comolli
doaj   +1 more source

INTERNATIONAL TRADE DURING THE CRISIS. DETERMINANTS [PDF]

open access: yesCES Working Papers, 2014
This article aims to analyze how the financial crisis that bursted in the mid-2008 led to a global and regional drop in trade flows. It starts from a comparison of the Great Depression shock to what happened during the Great Recession.
Cristian Spiridon
doaj  

Left-Wing Governmental Alliance in Portugal, 2015-2019: A Way of Renewing and Rejuvenating Social Democracy?

open access: yesBrazilian Political Science Review, 2021
The 2015-2019 left-wing government alliance in Portugal merits attention for several reasons, of which four stand out. First, because, if it worked well, it may offer a solution to the crisis affecting social-democratic parties by pushing them back to ...
André Freire
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

(WP 2017-02) The Great Recession and Public Education [PDF]

open access: yes, 2017
We examine the impact of the Great Recession on K-12 education finance and employment and generate five key results. First, nearly 300,000 school employees lost their jobs. Second, schools that were heavily dependent financially on state governments were
Evans, William N.   +2 more
core   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Unemployment in the Great Recession: single parents and men hit hard [PDF]

open access: yes, 2011
This brief discusses the sweeping impact the Great Recession has had on Americans, particularly men, single parents, young adults, and people with less education.
Bean, Jessica A.   +2 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The Hidden Cost of the Recession: Two Million Fewer Births and Still Counting [PDF]

open access: yes, 2014
The Great Recession sent an economic shock through American society that reached far beyond the stock and housing markets, including the substantial long-term impact the Great Recession is having on U.S. births.
Johnson, Kenneth M.
core   +1 more source

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