Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Research on weak greedy routing over graph embedding for wireless sensor networks
The greedy routing in sensor networks can be classified into two categories,strong greedy routing and weak greedy routing.The weak greedy routing protocol needs geographic location and strong greedy routing needs greedy em-bedding network.In order to ...
LI Zhi-gang1 +3 more
doaj +2 more sources
Greedy and $K$-Greedy Algorithms for Multidimensional Data Association [PDF]
This research was supported by a Marie Curie fellowship of the European Community program "Improving Human Research Potential and the Socio-economic Knowledge Base" under Contract HPMI-CT-2002-00221.
Perea Rojas Marcos, Federico +1 more
openaire +2 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones +3 more
wiley +1 more source
Implementasi Algoritma Greedy pada Pencarian Langkah Optimal Permainan Mahjong Solitaire
The game of mahjong solitaire is a difficult tough teaser and takes a long time to complete when manually played by the user. The greedy algorithm is applied to find the optimal step in completion of this solitaire mahjong game.
Alvin Juvianto, Halim Agung
doaj +1 more source
Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow +4 more
wiley +1 more source
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Connected greedy colourings of perfect graphs and other classes: the good, the bad and the ugly [PDF]
The Grundy number of a graph is the maximum number of colours used by the "First-Fit" greedy colouring algorithm over all vertex orderings. Given a vertex ordering $\sigma= v_1,\dots,v_n$, the "First-Fit" greedy colouring algorithm ...
Laurent Beaudou +6 more
doaj +1 more source

