Results 161 to 170 of about 714 (240)

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai   +7 more
wiley   +1 more source

Graph Neural Networks for Maximum Constraint Satisfaction. [PDF]

open access: yesFront Artif Intell, 2020
Tönshoff J, Ritzert M, Wolf H, Grohe M.
europepmc   +1 more source

Greedy k-improper coloring

open access: gold, 2020
Efraim Naassom Helem Dantas Rodrigues
openalex   +1 more source

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes at Aβ‐PET Centiloid 15, Mean Age of 66 Years

open access: yesAnnals of Neurology, EarlyView.
Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas   +29 more
wiley   +1 more source

Electromembrane Extraction for Multiclass Pesticide Assessment in Soil Matrices: Sustainable Analytical Insights

open access: yesAnalysis &Sensing, EarlyView.
The U‐shaped electromembrane extraction with liquid chromatography‐mass spectrometry enables rapid multiclass pesticide screening in soil. The 15 min, low‐solvent workflow achieves high recoveries and robust linearity, while AGREEprep and GAPI assessments highlight a greener profile compared to literature reports, which represents a smart strategy for ...
Rafael O. Martins   +9 more
wiley   +1 more source

Two distinct trajectories of brain volume loss in myotonic dystrophy type 1 via machine learning. [PDF]

open access: yesBrain Commun
Imokawa T   +9 more
europepmc   +1 more source

Mechanochromic Organic Materials: Molecular Mechanisms and Multidimensional Applications

open access: yesAdvanced Physics Research, EarlyView.
Mechanochromic (MC) organic materials change color in response to mechanical force. This review elucidates the molecular mechanisms (e.g., aggregation‐induced emission, AIE) and explores their multidimensional applications in sensors, anti‐counterfeiting, biomedical devices, and structural health monitoring, providing a roadmap for future smart ...
Xiaozhe Yin   +5 more
wiley   +1 more source

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

open access: yesThe Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum   +3 more
wiley   +1 more source

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