Results 91 to 100 of about 48,754 (287)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The Local Formulation for the Modified Green's Function Method

open access: yesLatin American Journal of Solids and Structures
The Modified Global Green's Function Method (MGGFM) is an integral technique that is characterized by good accuracy in the evaluation of boundary fluxes.
Renato Barbieri   +1 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

STRONG SHORT-RANGE INTERACTIONS IN ONE-DIMENSIONAL PROTON CONDUCTOR

open access: yesCondensed Matter Physics, 2003
The behaviour of one-dimensional proton conductor is investigated on the basis of orientational-tunnelling model. The previously proposed technique which permits the proton interactions to be taken into account in the zero-order Hamiltonian, and is based
I.V.Stasyuk, O.Vorobyov
doaj   +1 more source

Computing the Many-Body Green's Function with Adaptive Variational Quantum Dynamics. [PDF]

open access: yesJ Chem Theory Comput, 2023
Gomes N, Williams-Young DB, de Jong WA.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

REDUCED p-MODULUS, p-HARMONIC RADIUS AND p-HARMONIC GREEN’S MAPPINGS

open access: yesПроблемы анализа, 2018
We consider the definitions and properties of the metric characteristics of the spatial domains previously introduced by the author, and their connection with the class of mappings, the particular case of which are the harmonic Green’s mappings ...
B. E. Levitskii
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy