Results 141 to 150 of about 4,094,541 (315)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
3D dust map from Green et al. (2017)
A three-dimensional map of dust reddening, covering the three quarters of the sky surveyed by the Pan-STARRS 1 (PS1) survey. We use PS1 and 2MASS optical and near-infrared photometry to infer distances and reddenings to ~800 million stars.
Green, Gregory
core +2 more sources
Letter from Grandpa and Ma to Smith Green
, 1945 Letter from William and Mary Green to their grandson, Smith Green, giving updates.Broken Bow, Okla Nov. 13th, 1945. Dear Smith We got your letter yesterday and also one from Virginia, the day before. So will write and both of you can read it.
Green, William M., Green, Mary D.
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Bill Green and relatives or friends
, 1937 Black and white photograph of William Manning Green and several friends or relatives, probably in Ogden, Utah, in the late 1930s. Left to right: Bill Green, his mother (born Effie Margaret Chapman); "Flossie," step-father Frederick Maynes, "Ma" Anderson,
Green, William M. (William Manning), 1916-2007
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 1937 Black and white photograph of William Manning Green at Blacker House (residence for undergraduates) at the California Institute of Technology, Pasadena, in the late ...
Green, William M. (William Manning), 1916-2007
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
View toward East and Sandias from Green House
, 1950 View looking East toward the Sandias from the Green House (249 Old Church ...
Green, John
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source