FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A Müller Glia-Retinal Pigment Epithelium Apical Network Surrounding Cone Outer Segments in Fish and Mouse. [PDF]
GliaSharkova M +6 more
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Letter from Smith Green to grandma and grandpa
, 1939 Letter from Smith Green to his grandparents, William and Mary Green, giving updates.Ft. Sam Houston July 31, 1939 Dear Grandma and Grandpa, I rec't yours and Aunt Lucia's letter a few days ago and of course was glad to get it.
Green, Smith Lowry
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The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
D5.4 – Final OSED – Green Route Charging
Green-GEAR aims at enabling and incentivising optimum green trajectories and airspace use through new ATM procedures; it develops three new SESAR Solutions to this end.
Bolic, T.
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Wallace Green at wheel of car, Devils Elbow, Mt Wilson, New South Wales, 1946 [picture] /
, 1946 Part of John Falloon collection.; Inscriptions: "J.F. 249 Wallace H Green (photographer) at wheel of car, Devils Elbow, Mt Wilson, 1946"--In on verso.; Title devised by cataloguer from inscription on verso.; Also available online at: http://nla.gov.au ...
Green, Wallace.
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Comparative biochemical analysis of tea (<i>Camellia sinensis</i>) and coffee (<i>Coffea arabica</i>) extracts identifies the ethyl acetate fraction of green tea as a potential dual digestive enzyme inhibitor: an <i>in vitro</i> and <i>in silico</i> study. [PDF]
RSC AdvEl-Saied YE +5 more
europepmc +1 more source