Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Bio-inspired chemometric methods for simultaneous UV spectrophotometric determination of molnupiravir, nirmatrelvir, and favipiravir in pharmaceutical formulations and environmental samples. [PDF]
Abdelzaher AM, Al Kamaly O, Rahman MAA.
europepmc +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Development of a green chemistry based bioanalytical method using response surface methodology to analyze febuxostat and indomethacin in rabbit plasma. [PDF]
Ansary A +7 more
europepmc +1 more source
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Green RP-HPLC method for estimation of trigonelline: AQbD based development, validation, and application to nanoformulations. [PDF]
Kothapalli P, Vasanthan M.
europepmc +1 more source
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Highly fluorescent method for ultra-sensitive estimation of delafloxacin in human plasma: greenness assessment. [PDF]
Salman BI.
europepmc +1 more source
Hydrophobic Deep Eutectic Solvent in Vortex-Assisted Liquid-Liquid Microextraction for Pesticide Analysis by Gas Chromatography. [PDF]
Taweetanawikai N, Boonchiangma S.
europepmc +1 more source
Sensitive voltammetric detection of bosentan using gold nanoparticles-decorated pencil graphite electrode in pharmaceutical formulations and plasma samples. [PDF]
Trabik YA +4 more
europepmc +1 more source

