Results 271 to 280 of about 564,980 (339)

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Sustainable Extraction of Alkaloids from <i>Worsleya procera</i>: Improving the Method with Green Chemistry. [PDF]

open access: yesACS Omega
Duque Rodrigues W   +5 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Sustainable RP-UPLC analysis of Nirogacestat for desmoid tumors using quality-by-design and green analytical chemistry

open access: gold
Goud, Vanga Mohan   +4 more
openalex   +1 more source

MALDI-TOF MS-Based Lipidomic Profile of Honey and Bee Pollen. [PDF]

open access: yesACS Agric Sci Technol
Jano A   +5 more
europepmc   +1 more source

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