Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Research on sustainable green building space design model integrating IoT technology. [PDF]
PLoS OneWang Y, Liu L.
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Towards sustainable architecture: Enhancing green building energy consumption prediction with integrated variational autoencoders and self-attentive gated recurrent units from multifaceted datasets. [PDF]
PLoS OneZeng Q, Peng F, Han X.
europepmc +1 more source
Pruning chemicals from the green building landscape. [PDF]
J Expo Sci Environ Epidemiol, 2020 Goodwin Robbins LJ +4 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Active learning-based machine learning approach for enhancing environmental sustainability in green building energy consumption. [PDF]
Sci RepMahmood S +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Navigating dual pressures: The impact of environmental policies and market demand risks on the sustainable development of green building materials - A case study of the green cement industry. [PDF]
HeliyonGuo W.
europepmc +1 more source