Results 161 to 170 of about 816,580 (291)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Climate-adaptive energy forecasting in green buildings via attention-enhanced Seq2Seq transfer learning. [PDF]

Sci Rep
Peng F, Su T, Zeng Q, Han X.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Building Green

, 2023
How developing countries meet their rising building needs will be pivotal to the world’s climate future. The good news is that the projected emissions growth in construction value chains can be reduced significantly with the application of existing technologies, new financing instruments, and ...
openaire   +1 more source

Heat kernel and Green function estimates on affine buildings

, 2013
We obtain the optimal global upper and lower bounds for the transition density $p_n(x,y)$ of a finite range isotropic random walk on affine buildings.
Trojan, Bartosz
core  

On-Going into Green Buildings: Hybridized Bimetallic Iron Ferrite Scheme for Superior Performance in a Pilot-Scale Solar Energy Storage System. [PDF]

ACS Omega
Nour MM, Tony MA, Nabwey HA.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Smart green and healthy buildings [PDF]

, 2015
Sekhar, Chandra, Toftum, Jørn, Wai, David Cheong Kok   +2 more
core   +1 more source

Multifunctional and Environmentally Friendly TiO₂-SiO₂ Mesoporous Materials for Sustainable Green Buildings. [PDF]

Molecules, 2019
Ghedini E, Menegazzo F, Manzoli M, Di Michele A, Puglia D, Signoretto M.   +5 more
europepmc   +1 more source