Results 31 to 40 of about 121,790 (258)

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel, Santiago Pérez‐Hoyos, Aroa Soriano, Ana Coma, Amalia Varo, Raquel Hladun, Gabriela Guillén, Soraya Mico, Marta Garrido, Lourdes Rubio, Alba Rubio‐San‐Simón, Ana Minguez, Ricardo López‐Almaraz, Laura Illade, Miguel F. Segura, Lucas Moreno   +15 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Green@Universiti Putra Malaysia: cultivating the green campus culture

E3S Web of Conferences, 2018
This article highlights the University’s strategic plan and institutionalization commitment in cultivating the green campus culture encircling the Green@UPM initiative.
Aris Ahmad Zaharin Aris, Ponrahono Zakiah, Ishak Mohd Yusoff, Zamaruddin Nor Hazlina, Noordin Nor Kamariah, Varatharajoo Renuganth, Ideris Aini   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The Qur’ānic Green Campus Model in Islamic Higher Education Indonesia

Studia Ecologiae et Bioethicae
This paper aims to explore the concept of Qur’ānic ecology and its relevance to the green campus concept in Islamic Higher Education Indonesia. This research is a qualitative with object study green campus practices at Universitas Islam Negeri (UIN ...
Abdul Fatah, Mochamad Tholib Khoiril Waro   +1 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Eco Green Campus: Challenges and Opportunities. The Study Case of Polytechnic Institute of Beja [PDF]

E3S Web of Conferences, 2020
Higher Education Institutions have an important role in the promotion of sustainability. The sustainability has been seen not only as a component of education, research and innovation, but also as a social learning process within and beyond academia. The
Pardal Ana, Romeira Telma, Durão Anabela   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Exploring students’ perception of green creative behaviour in higher education to support climate change mitigation and SDGs [PDF]

E3S Web of Conferences
Higher education supports SDG 13 (Climate Action) through green campus programs. The green campus program is one of the mitigation program for climate change and increase students’ awareness of green behaviour on campus.
Windasari, Purwoko Budi, Habibie Ramadhan Kurnia, Ariyanto Restu Dwi, Sivapalan Subarna   +4 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source