Results 71 to 80 of about 3,892,985 (289)

In vivo image of glial cells for Fig 6A (green channel)

open access: yes, 2016
This image of glial cells deep in the cortex of a live GFAP-GFP mouse was acquired through an implanted GRIN lens using a multiphoton microscope. We believe this is one of the first in vivo images of glial cells this deep in the brain in the lower layers
Teresa Murray (815461)
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Converting TREx-RGB green-channel data to 557.7 nm auroral intensity: Methodology and initial results

open access: yesEarth and Planetary Physics
The recently deployed Transition Region Explorer (TREx)-RGB (red-green-blue) all-sky imager (ASI) is designed to capture “true color” images of the aurora and airglow.
Jun Liang   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Validation of Skin Perfusion Monitoring by Imaging PPG versus Laser Speckle Imaging

open access: yesCurrent Directions in Biomedical Engineering, 2023
Assessment of skin perfusion can reveal signs of deterioration and help to prevent critical states. Commonly applied clinical tests to capture skin perfusion are subjective and often hard to quantify.
Fleischhauer Vincent   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Community Green Map Detroit

open access: yes, 2003
A map of a small area of Detroit done by children, which includes descriptions and photographs of the community gathering that produced the ...
Detroit Green Map Team
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Channel Selection Strategies of Chinese E-Commerce Supply Chains Under Green Governmental Subsidies

open access: yesSystems
In the era of the green digital economy, network platforms as a new form of economic format have gained significant attention from e-commerce companies.
Lingyu Gao, Xiaoli Wang, Xu Xin
doaj   +1 more source

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