Results 61 to 70 of about 2,995,515 (299)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Optical wireless for intravehicle communications : a channel viability analysis [PDF]

open access: yes, 2012
This paper provides an initial analysis into the viability of implementing an optical wireless system for intravehicle communications. Based on the use of a simple linearly scalable infrared light-emitting-diode transmitter, the results for received ...
Mark S. Leeson   +5 more
core   +1 more source

G7 Green Gummies France Avis - Green Gummies Commentaires Avantages Prix, acheter

open access: yes, 2023
<p>G7 Plus Gummies France Avis Les « Green Gummies » sont un complément alimentaire conçu pour favoriser la perte de poids. Ces compléments visent à stimuler le métabolisme, à intensifier la combustion des graisses et à optimiser le bien-être ...
G7 Green Gummies
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Sustainable walking tour of the East Village

open access: yes, 2011
A map of the East Village area of New York City showing sites of interest for sustainability and social innovations.
Green Map System (Firm)
core   +1 more source

Green technology investment and channel selection in sustainable food supply chain based on blockchain technology

open access: yesFrontiers in Sustainable Food Systems
In the context of rapidly rising consumer demand for green food, this paper aims to systematically examine how green technology investment and blockchain technology influence the channel selections and operational decisions of members in the sustainable ...
Yuting Zhang, Juan Shang
doaj   +1 more source

Multi-user indoor optical wireless communication system channel control using a genetic algorithm [PDF]

open access: yes, 2011
A genetic algorithm controlled multispot transmitter is demonstrated that is capable of optimising the received power distribution for randomly aligned single element receivers in multiple fully diffuse optical wireless communications systems with ...
M.S. Leeson   +7 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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