Results 111 to 120 of about 3,892,985 (289)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Red (660 nm) or near-infrared (810 nm) photobiomodulation stimulates, while blue (415 nm), green (540 nm) light inhibits proliferation in human adipose-derived stem cells

open access: yesScientific Reports, 2017
We previously showed that blue (415 nm) and green (540 nm) wavelengths were more effective in stimulating osteoblast differentiation of human adipose-derived stem cells (hASC), compared to red (660 nm) and near-infrared (NIR, 810 nm).
Yuguang Wang   +4 more
doaj   +1 more source

Green Wi-Fi Management: Implementation on Partially Overlapped Channels

open access: yesIEEE Transactions on Green Communications and Networking, 2018
The channel assignment in the non-overlapped channel space may result in low spatial utilization and non-uniform Wi-Fi performance, which makes it difficult to cater to the rapid increase in Wi-Fi devices as well as wireless traffic demand. In this paper, we propose a Green Wi-Fi management framework for an enterprise environment in order to densely ...
Yaodong Zhang   +5 more
openaire   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

V-Mail

open access: yes, 1945
Address cover of a censored V-Mail letter from William Green, from "somewhere in France" to his mother in Lincoln, Nebraska ...
William Green
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Selective RGB Channel Jittering for Robust Endoscopic Disease Detection Across Multiple Lesion Types

open access: yesSakarya University Journal of Computer and Information Sciences
Deep learning has significantly advanced medical image analysis, particularly in the field of endoscopic images. However, these advancements are constrained by the availability of high-quality, annotated medical datasets.
Duygu Cakır
doaj   +1 more source

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