Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Recent developments in one-pot stepwise synthesis (OPSS) of small molecules
iScience, 2022 Summary: One-pot synthesis is an active topic in organic chemistry due to its intrinsic advantages of simple operation, high mass efficiency, low cost, and less amount of waste disposal.
Xiaoming Ma, Wei Zhang
doaj
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
iScience, 2022 Summary: Aromatic azo dyes are of immense commercial importance, and the development of greener routes for their synthesis is imperative due to current environmental concerns.
Ankit Thakuri +2 more
doaj
Applying Green Chemistry Principles in the Electrophilic Bromination of Indole-3-Acetic Acid [PDF]
, 2014 The goals of green chemistry are to reduce or eliminate the use of hazardous reagents, prevent the synthesis of toxic products and byproducts, and improve the overall efficiency of chemical reactions.
Murphy, Kyle
core +1 more source
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source
A System of Physical Chemistry . By W. C. McC. Lewis. New York: Longmans, Green, and Co., 1915. 19 × 13 cm.; 2 vols. Pp. vii + 552; xiv + 523. Price $2.50 net, each volume. [PDF]
, 1916 Wilder D. Bancroft
openalex +1 more source
A biorenewable cyclobutane-containing building block synthesized from sorbic acid using photoenergy
iScience, 2022 Summary: A novel cyclobutane-containing diacid building block, CBDA-3, was synthesized from sorbic acid using clean, efficient [2 + 2] photocycloaddition.
Micah Mabin +4 more
doaj
Penerapan Pendekatan Konstruktivisme Berorientasi Green Chemistry untuk Meningkatkan Keterampilan Berpikir Kritis dan Hasil Belajar Kimia SMA [PDF]
, 2015 Learning chemistry require laboratory work to support good teaching and learning process. SMA Muhammadiyah plus Salatiga is the limited number of laboratory and chemicals are available resulting in chemistry learning process is not managed well. Critical
Astuti, A. P. (Andari)
core
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source