Results 111 to 120 of about 1,652,756 (337)

Aspectos do conhecimento pedagógico do conteúdo de química verde em professores universitários de química

Educación Química, 2018
PCK aspects of Green Chemistry in university chemistry teachers This paper aims to document the pedagogical content knowledge (PCK) about Green Chemistry (GC) in professors from the Institute of Chemistry of the University of São Paulo, experts from ...
Luciane Fernandes de Goes, Sérgio Henrique Leal, Paola Corio, Carmen Fernandez   +3 more
doaj   +1 more source

Perangkat Pembelajaran Problem Based Learning Berorientasi Green Chemistry Materi Hidrolisis Garam Untuk Mengembangkan Soft Skill Konservasi Siswa [PDF]

, 2014
Penelitian ini bertujuan untuk mengembangkan perangkat pembelajaran problem based learning berorientasi green chemistry pada materi hidrolisis garam untuk mengembangkan soft skill konservasi siswa SMA.
Marwoto, P. (P), Rosita, A. (A), Sudarmin, S. (Sudarmin)   +2 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Engaging students for meaningful chemistry learning through microcomputer-based laboratory (MBL) inquiry : Promoure en els estudiants l’aprenentatge significatiu de la química mitjançat treballs pràctics indagatius amb l’ús d’equips de captació de dades amb sensors (MBL) [PDF]

, 2011
The Microcomputer-based Laboratory (MBL) can be an example of a student-centered learning environment that provides new opportunities to engage secondary-level chemistry students in meaningful learning and higher-order thinking through inquiry.
Aksela, Maija Katariina
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Integrating social and environmental justice into the chemistry classroom: a chemist’s toolbox

Green Chemistry Letters and Reviews, 2019
Although the chemical enterprise has provided numerous contributions to humanity, unintended consequences contribute to a disproportionate exposure of hazardous chemicals to certain populations based on race and socioeconomic status. Integrating concepts
Grace A. Lasker, Edward J. Brush
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Principles of green chemistry: building a sustainable future

Discover Chemistry
Green chemistry is an interdisciplinary field that focuses on minimizing hazardous substances and promoting sustainable alternatives in chemical processes to conventional chemical processes and products.
Fatma Kurul, Beyzanur Doruk, Seda Nur Topkaya   +2 more
doaj   +1 more source