Results 141 to 150 of about 5,045,211 (295)

Increased yields in alkaline pulping I: a study of the peeling reaction at the conditions of kraft puling. Project 2942, report three : a progress report to members of group project 2942

open access: yes, 1972
"The Institute of Paper Chemistry, John W. Green. senior research associate, Division of Natural Materials and Systems.""April 26, 1972.
Green, John W.
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Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Green Chemistry in Government and Industry/ Edited by Mark Anthony Benvenuto and Heinz Plaumann.

open access: yes, 2020
In English.The 5th volume of Green Chemical Processing considers sustainable chemistry in the context of governmental and corporate interests, explaining how "red tape" can help or hinder the "greening" of industry processes.
Plaumann Heinz, Benvenuto Mark Anthony
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Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Green Chemistry [PDF]

open access: yesChemistry International -- Newsmagazine for IUPAC, 2007
Martyn Poliakoff, Pete Licence
  +4 more sources

Green Chemistry Education: Recent Developments Green chemical processing ;, vol. 4./ Mark Anthony Benvenuto and Larry Kolopajlo.

open access: yes, 2019
In English.Includes bibliographical references and index.Kolopajlo, Larry / Benvenuto, Mark -- Noce, Anthony M. -- Berger, Michael / Karod, Madeline / Goldfarb, Jillian L. -- Sadraei, S. Iraj / Onge, Brent St / Trant, John F.
Krikke James.   +23 more
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