Results 171 to 180 of about 1,652,756 (337)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Sustainable green chemistry

open access: yesGreen Processing and Synthesis, 2017
Morales Gonzalez Olivia Maria
doaj   +1 more source

Sustainable Extraction of Alkaloids from <i>Worsleya procera</i>: Improving the Method with Green Chemistry. [PDF]

open access: yesACS Omega
Duque Rodrigues W   +5 more
europepmc   +1 more source

Chemists and the School of nature

open access: yes, 2002
International audienceBiomimetism is an umbrella covering a variety of research fields ranging from the chemistry of natural products to nanocomposites, via biomaterials and supramolecular chemistry. . It is an informal movement and the concept itself is
Arribart, Hervé   +3 more
core   +1 more source

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