The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Monomeric, Oligomeric, Polymeric, and Supramolecular Cyclodextrins as Catalysts for Green Chemistry. [PDF]
Komiyama M.
europepmc +1 more source
The development of an environmentally benign sulfideoxidation procedure and its assessment by green chemistry metrics [PDF]
Claudio O. Kinen+2 more
openalex +1 more source
Advancements in green chemistry: sustainable synthesis and processes
An emerging area of chemistry called «green chemistry» is revolutionising how environmental and sustainability issues related to chemical synthesis and processes are handled.
Хамфри Сэм Сэмуэль+3 more
doaj
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Linking mechanochemistry with the green chemistry principles: Review article. [PDF]
Arfelis S+8 more
europepmc +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Editorial: Green chemistry to recycle Fe/C-rich wastes for environmental pollution control. [PDF]
Suiyi Z, Wei F, Xinfeng X, Temuujin J.
europepmc +1 more source
Exposed: The Toxic Chemistry of Everyday Products and What’s at Stake for American Power by Mark Schapiro . White River Junction, VT:Chelsea Green, 2007. 224 pp. ISBN: 978-1-933392-15-8, $22.95 [PDF]
C.W. Jameson
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In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source